Can I copyright my end design?

Using the Graphics

Unfortunately not. It's not possible to copyright or trademark the work you create using Graphic Resources purchased from www.lisaglanz.com as the ownership and copyright of the items belong solely to Lisa Glanz, the original designer. When you purchase a graphic/illustration/pattern from Lisa Glanz, you are agreeing to a non-exclusive and non transferable licence which does not allow for copyrighting or trademarking.

Using the Procreate brushes

Yes absolutely. Any original artwork you create using Procreate brushes purchased from www.lisaglanz.com belongs to you. Which means you, the original creator of that artwork, are the copyright owner. The Procreate brushes are like any other art supply you would purchase at an art store to create your own art with. These are just in digital form.